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KMID : 0379119840120030117
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Korean Journal of Mycology
1984 Volume.12 No. 3 p.117 ~ p.119
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Studies on Constituents of the Higher Fungi of Korea (48)
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Abstract
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To find toxic components in Korean higher fungi, the carpophores of Naematoloma fasciculare which had caused several cases of lethal intoxication were examined for toxicity. The components of high molecular weight were separated by ethanol precipitation and dialysis from the aqueous extract of the carpophores. After the components were freeze-dried, a brown powder was obtained. When a dose of 60㎎/㎏ of this macromolecular fraction was intraperitoneally injected into mice, the mice began to die in six days and a half of them died within seven days. This toxic component was named nematoxin after the genus name of the mushroom.
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